The World Health Organization (WHO) used 1000minds to prioritize endemic pathogens for vaccine research and development (R&D) and better align investments with evidence and stakeholder perspectives around the world.
This project supports the WHO’s Immunization Agenda for 2030 (IA2030), which seeks to “create a world where everyone, everywhere, at every age fully benefits from vaccines for good health and well-being”. The prioritized list of pathogens can be used to guide public health officials and other leaders regionally and globally in developing immunization programs and setting priorities.
Pathogen prioritization was done using multi-criteria decision analysis (MCDA), facilitated by 1000minds. This process involved identifying prioritization criteria and pathogens to be prioritized based on existing literature and precedents. These criteria were then weighed using 1000minds surveys, which use the PAPRIKA method to elicit stakeholder judgements regarding the relative importance of criteria.
This approach fulfills the IA2030 principles emphasizing inclusivity and being data-centered. The ability to translate 1000minds surveys allowed surveys to be sent out in major languages of each region, while MCDA provided a structured, systematic approach that minimized bias.
The final list of 17 global priorities and the associated 34 vaccine use cases were endorsed by WHO’s Product Development for Vaccines Advisory Committee.
Further reading
- M Hasso-Agopsowicz, A Hwang, M Hollm-Delgado et al (2024), “Identifying WHO global priority endemic pathogens for vaccine research and development (R&D) using multi-criteria decision analysis (MCDA): an objective of the Immunization Agenda 2030”, EBioMedicine 110, 105424
Share this post on:
